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연구실소개
연구실소개
 정보광장 연구실소개 유기계면공학 연구실
유기계면공학 연구실(Organic Interface Engineering Lab.)
연구실 소개
Welcome to the Organic Interface Engineering Lab. in the Seoul National University of Science and Technology. We work in the field that is focused on developing technologies based on nanotechnology. This highly interdisciplinary research group works in the field of science at the interface between physics, chemistry and biology.
연구분야
Biophysics of interfaces
The cell membrane, the interface between the cell and its environment, is the functional element in cellular metabolism and signaling. A great deal is found about the lipid, protein and saccharide constituents of membranes and their organization, and the physical properties are related with structures and functions.
A model has been utilized to study the physical properties of the cell membranes in which (glyco) proteins such as integrins, selectins, and lectins are involved in cellular interactions. On the other hand, direct measurements of the surface forces between lipid bilayers of phosphatidylethanolamine, phosphatidylcholoine, and galactolipids, the most common lipids in animal and plant membranes, suggest strong repulsive forces between highly hydrated head groups, which prevent membranes from coming into contact and reacting, adhering or fusing. Much could be known about the function and organization of the membrane's constituents if the physical properties of membranes could be measured with nanometer scale lateral resolution.
Biosensing devices
Early detection of infectious diseases is important to enhance the quality of medical care and limit the spread of emerging infectious diseases. Thus, there is a need for rapid, sensitive, and inexpensive point-of-care sensors that have capability to identify multiple pathogens in complex samples such as blood. Novel techniques have been developed for sensing pathogens, based on microfluidics. Eventually, the techniques will be platform for high throughput with low sample volume reagents and highly selective analyte sensing. These assays are designed to abstract molecular level details and mechanistic insights from biophysical and bioanalytical problems that would otherwise be difficult to approach.
담당교수: 박진원(02-970-6605)
연구실 위치: 청운관 110호
연구실 전화: 02-970-9910

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