학과소개

교수소개
 학과소개 교수소개
이름 노인섭
전공 생체재료, 국부적 물전달, 3D 바이오프린팅 조직공학
 
TEL 02-970-6603
E-mail insup@seoultech.ac.kr
연구실 청운관 219호
 
교수소개 돌아가기

학력

1992 - 1994 Univ. of Texas at Austin / Ph.D.(1997) Dr. Jeffrey A. Hubbell's Lab
1989 - 1997 Univ. of Texas at Austin / MSE (1995) Dr. Jeffrey A. Hubbell's Lab
1981 - 1989 Konkuk University / BS

주요 경력

1. Education
2010 - Present
Department of Chemical and Biomolecular Engineering, Energy & Biotechnology College
Convergence Institute of Biomedical Eng. and Biomaterials ( Ph.D. and MS degree program, General Graduate School)
Convergence program of Biomedical Science and Technology (Master degree program, Industrial Graduate School)
Seoul National University of Science and Technology / Professor
1999 - 2010 Seoul National University of Technology / Associate/Assistant Professor/Full Time Instructor
1997 - 1999 Division of Harvard Univ.-MIT Health Science and Tech.(Postdoc, Dr./M.D. Elazer R. Edelman's Lab)
1995 - 1997 California Institute of Technology(Dept. of Chemical Eng., Special Graduate Student)

2. Careers
1) Military Service
2) Modern Tissue Technology / Scientific Advisor (2001 - 2005)
3) Modern Cell & Tissue Technology / Scientific Advisor (2005 - 2006)
4) Presidential Council of Intellectual Properties, 국가지식재산위원회 활용분과위원 (2011- present)
5) Professional Society
- Korea Society for Biomaterials(vice President; 2014-Present)
- Korea Tissue Engineering and Regenerative Medicine Society (Vice President; 2015-Present)
- Korea Polymer Society (Biomedical Polymers Division Chief; 2016-Present)
- Korea 3D Printing Society (2017-Present)
6) Editor-in-chief
- Biomaterials Research (BiomedCentral, Springer-Nature)(2014-present)
- Open Biomedical Engineering (Asian Editor-in-Cheif, 2015-Present)
- Biomedical Central, BMC Editors Advisory Board (2015-Present)
7) Editorial board members
- Biomedical Materials (SCIE)(IOP)
- Tissue Engineering and Regenerative Medicine (SCIE) (Springer, 2008-Present)
- International Biological & Biomedical Journal (2015-Present)
8) 중앙약사심의위원회 전문가. 식품의약품안전청(처) (2006-2014)
9) 산업통상자원부 전략물자관리원, 심의위원 (2006-present)
10) 신기술(NET) 심의위원
11) 소방방재청 중앙소방기술 심의위원 (2011.06.01.-)
12) Director of Institute for Biomedical Electronics, Seoultech (2011-present)

연구 분야

- Biomaterials (Polymers)
- Injectable hydrogels for bioprinting and tissue engineering
- 3D Bioprinting and its Biomaterials
- Polymer-ceramic hybrid hydrogel
- Scaffolds for tissue engineering
- Local drug delivery
- Tissue engineering
- Nano-micro biotechnology
- Stem Cells Applications

주요논문 및 저서

Recent Publications
81. Sumi Kim, Yoonjung Choi, Kuk Hui Son, Yong-doo Park, Yong Hu Fang and Insup Noh, “Tissue regeneration in the pores of poly(lactide-co-glycolide)-impregnated wall of expanded polytetrafluoroethylene (ePTFE) hybrid grafts”, Tissue Eng Regen Med, 11(4), 1-10 (2014)
82. Sungchul Choi, Miae Yoo, Donghoon Son, Jessica Jung, Insup Noh and Chan-Wha Kim, Effects of cross-linking agent on the rheological and anti-inflammatory properties of hyaluronic acid hydrogel
83. Kim KB, Kim H, Song EJ, Kim S, Noh I, Kim C. A cap-type Schiff base acting as a fluorescence sensor for zinc(II) and a colorimetric sensor for iron(II), Dalton Transactions, 42(2013) 16569-16577
84. Nam Hee Kim, Yong Hoon Cha, Hyun Sil Kim, Soo Eon Lee, Jong Ki Heo, Jung Kook Kim, Jeong Moon Kim, JooKyung Ryu, So Young Cha, Yoonmi Lee, Soo Yeon Lee, Insup Noh, Xiaoyan Li, Stephen J Weiss, Tae Ahn Jahng, Jong In Yook, A simple platform for growth factor delivery with novel mode of action, Biomaterials, 35(2014) 9888-9896
85. A single fluorescent chemosensor for multiple target ions: Recognition of Zn2+ in 100% aqueous solution and F- in organic solvent, Song, E.J., Kim, H., Hwang, I.H., Kim, K.B., Kim, A.R., Noh, I., Kim, C. Sensors and Actuators B: Chemical Volume 195, (2014) pp. 36-43 (IF 3.535)
86. A single chemosenosor for multiple analytes: fluorogenic detection for Zn2+ and OAc-ions in aqueous solution, and an application to bioimaging" Gyeong Jin Park, Yu Jeong Na, Hyun Yong Jo, Seul Ah Lee, Ah Ram Kim, Insup Noh and Cheal, New Journal of Chem, 38(2014-03), 2587-2594
87. Purification and Biocompatibility of Fermented Hyaluronic Acid for Its Applications to Biomaterials, Sungchul Choi, Woncheol Choi, Sekweon Kim, SuYeon Lee, Insup Noh and Chan-Wha Kim, Biomaterials Research, (2014-06-25) 18, 6
88. Editorial, Insup Noh (교신), Biomaterials Research, (2014.06.), 18, 4
89. Evaluation of the effects of Ag ion concentration on osteoblast activity, SB Cho, GJ Yoon, EM An, YJ Kim, TN Kim, HD Jang, JY Choi and I. Noh, Key Engineering Materials, 631 (2015) 390-394
90. A new multifunctional Schiff base as a fluorescence sensor for Al3+ and a colorimetric sensor for CN− in aqueous media: an application to bioimaging, Seul Ah Lee, Ga Rim You, Ye Won Choi, Hyun Yong Jo, Ah Ram Kim, Insup Noh, Sung-Jin Kim, Youngmee Kim and Cheal Kim, Dalton Transactions, 43 (2014) 6650-6659
91. Biological Evaluation of Micro-patterned Hyaluronic Acid Hydrogel for Bone Tissue Engineering, Pure and Applied Chemistry, H S Park, SY Lee, HS Yoon, and Insup Noh(corresponding), 86(12) (2014-09) 1911-1922
92. Hyaluronic Acid-based Hydrogel as a Scaffold for Tissue engineering, Handbook of Intelligent Scaffolds Chapter 9, 저서, 2014-08-11
93. A highly selective turn-on chemosensor capable of monitoring Zn2+ concentrations in aqueous solution and living cells, Gyeong J Park; Hyun Kim; Jae J Lee; Yong S Kim; Sun Lee; Insup Noh; Suyeon Lee, Cheal Kim, Sensors and Actuators B 215 (2015) 568–576
94. Modulation of biomechanical properties of hyaluronic acid hydrogels by cross-linking agents, Sungchul Choi, Miae Yoo, Su Yeon Lee, Hyunji Lee, Donghoon Son, Jessica Jung, Insup Noh* and Chan-Wha Kim*, 2015, J Biomed Mater Res A, 2015, 103(9):3072-80
95. Selective Zinc Sensor Based on Pyrazoles and Quinoline Used to Image Cells, Kim, Hyun; You, Ga Rim; Park, Gyeong; Choi, Ji Young; Noh, Insup; Kim, Youngmee; Kim, Sung-Jin; Kim, Cheal; Harrison, Roger, Dyes and Pigments, 723-729, 2015
96. A fluorescence sensor for Zn2+that also acts as a visible sensor for Co2+and Cu2+ Eun Joo Song, Gyeong Jin Park, Jae Jun Lee, Suyeon Lee, Insup Noh, Youngmee Kim, Sung-Jin Kim, Cheal Kim, Roger G. Harrison, Sensors and Actuators B, 213, (2015) 268–275
97. A water-soluble carboxylic-functionalized chemosensor for detecting Al3 in aqueous media and living cells: Experimental and theoretical studies Jae Jun Lee, Gyeong Jin Park, Yong Sung Kim, Sun Young Lee, Hyun Ji Lee, Insup Noh, Cheal Kim, Biosensors and Bioelectronics, 69, 226–229 (2015)
98. Frontiers in Regenerative Medical Materials(communication): Comments from the participants of the 2014 China–Korea Symposium on Biomimetic and Regenerative Medical Materials, Jun Ma*, Insup Noh*(equal contribution), In-Seop Lee, Shengmin Zhang, Regenerative Biomaterials, 2015 Feburary, 71-76.
99. A bimodal chemosensor for dual analytes: highly selective fluorescent sensing for Zn2+ and colorimetric sensing for Co2+ in fully aqueous solution, submitted (2015) Journal of Materials Chemistry C,
100. A dual chemosensor for Zn2+ and Co2+ in aqueous media and living cells: experimental and theoretical studies, Gyeong J Park; Jae J Lee; Ga R You; LeTuyen Nguyen; Insup Noh, Cheal Kim, Analytica Chimica Acta (2015-03-24)
101. Synthesis and in vitro characterization of porous carboxymethyl cellulose-poly(ethylene oxide) hydrogel film, Su Yeon Lee, Sumi Bang, Sumi Kim, Seong Yeon Jo, Bum-Chul Kim, Yunjae Hwang, Insup Noh, Biomaterials Research, (2015.04.23.), 19(12)
102. A highly selective CHEF-type chemosensor for monitoring Zn2+ in aqueous solution and living cells, Jae Jun Lee, Seul Ah Lee, Hyun Kim, LeTuyen Nguyen, Insup Noh and Cheal Kim, RSC Advances, 52, 5, 41905-41913(2015)
103. Evaluation of the effects of Ag ion concentration on osteoblast activity, S. B. CHO, G. J. YOON, E. M. AN Y. J. KIM, T. N. KIM,H. D. JANG, J. Y. CHOI and I. NOH, Key Engineering Materials Vol. 631 (2015) pp 390-394
104. Research Trends in Biomimetic Medical Materials for Tissue Engineering :–commentary, Biomaterials Research, Ki Dong Park†, Xiumei Wang†, Jae Young Lee, Kyung Min Park, ShengMin Zhang* and Insup Noh* (2016.03.29.), 20(8)
105. Research Trends in Biomimetic Medical Materials for Tissue Engineering : 3D bioprinting, surface modification, nano/micro-technology and clinical aspects in tissue engineering of cartilage and bone (mini-review), Cen Chen†, Sumi Bang†, Younghak Cho, Sahnghoon Lee, Inseop Lee,ShengMin Zhang and Insup Noh*, Biomaterials Research, (2016), 20(10)
106. Simultaneous bioimaging recognition of cation Al3+ and anion F- by a fluorogenic method, Yong Sung Kim, Jae Jun Lee **, Ye Won Choi, Ga Rim You, LeTuyen Nguyen, Insup Noh, Cheal Kim,* Dyes and Pigments, 129 43-53, ELSVIER (2016.06)
107. A highly selective and sensitive fluorescent turn-on Al3+ chemosensor in aqueous media and living cells: experimental and theoretical studies, In Hong Hwang, Ye Won Choi, Kyung Beom Kim, Gyeong Jin Park, Jae Jun Lee, LeTuyen Nguyen, Insup Noh and Cheal Kim* New Journal of Chemistry, Royal Society of Chemistry, New J. Chem., 2016,40, 171-178 (2016.)
108. Micro/Nano Surface Topography and 3D Bioprinting of Biomaterials in Tissue Engineering, Dian Purwita Sari, Sumi Bang, LeTuyen Nguyen, Younghak Cho, Ki Dong Park, Sahnghoon Lee, Inseop Lee, Shengmin Zhang, and Insup Noh, J. Nanosci. Nanotechnol. 16, 8909-8922 (2016.07)
109. Analysis of physical properties for various compositions of reusable LMG and LCG micelle gel, Jin Mook Kang, Dong Han Lee, Yu Ra Cho, Seon Bung Hwang, Young Hoon Ji, So Hyun Ahn, Ki Chang Keun, Re Na Lee, Sam Ju Cho, Insup Noh, Progress in Medcial Physics, 27(4), 175-179, Dec 2016

담당 교과목

Teaching Courses :
- Tissue Engineering (Graduate Courese)
- Introduction to Convergence of Biomedical Engineering and Biomaterials (Graduate Course)
- Functional Polymers (Graduate Courses)
- Intorduction to Polymer Science and Technology (Undergraduate Courese)
- Organic Chemistry (Undergraduate Course)
- Biomedical Engineering (Undergraduate Course)

저널 논문

1. Editor-in-chief
- Biomaterials Research (BiomedCentral, Springer-Nature)(2014-present)
- Open Biomedical Engineering (Asian Editor-in-Cheif, 2015-Present)
- Biomedical Central, BMC Editors Advisory Board (2015-Present)
2. Editorial board members
- Biomedical Materials (SCIE)(IOP) (2008- Present)
- Tissue Engineering and Regenerative Medicine (SCIE) (Springer, 2008-Present)
- International Biological & Biomedical Journal (2015-Present)

학술대회 발표

Recent
1. Evaluation of Hyaluronic Acid-Chondroitin Sulfate Hydrogel Contaning Platelet-Rich Plasma for Cartilage Restoration,Ah Ram Kim, Hyo Seung Park, Beom Chul Kim, Eun Kyung Shin, Soo Yeon Lee, Insup Noh, ICRBM 2013 Conference ,2013.06.02.-06.06. Wuhan, China,
2. Patterned Hyaluronic Acid Hydrogel for Tissue Engineering, Ahram Kim, Hyoseung Park, Sumi Kim, Suyeon Lee, Seungjin Oh, Bumchul Kim and Insup Noh , Nano Korea 2013, 2013.07.10. Coex, Seoul, Korea.
3. Poly(ethylene glycol Coating on the Polyethylene surface for prevention of biofilm Formation, SeungjinOh, BumchulKim, SuyeonLee, HyoseungPark, AhramKim, KwangsooLee, Hyunji Lee, Hyenwoo Byeon, Yungyeong Gu, Iae jun Song, Sung Min Kim, Dong Keun Han and Insup Noh , AESPE (20130825)August 15-30, 2013 Ramada Plaza Jeju Hotel , Jeju, Korea
4. Poly(ethylene glycol Coating for Reduction of Bacterial Adhension on Poly(dimethyl Siloxane)Substrate for Its applications in ventilation tubes, Seungjin Oh, Bumchul Kim, Suyeon Lee, Hyoseung Park, Ahram Kim, Kwangsoo Lee, Hyunji Lee, Hyenwoo Byeon, Yungyeong Gu, Iae jun Song, Sung Min Kim, Dong Keun Han and Insup Noh , AESPE (20130825)August 15-30, 2013 Ramada Plaza Jeju Hotel , Jeju, Korea
5. Effects of Cross-Linking Spacers on Nerve Cell Biocompatibility of Chitosan -Poly(ethylene oxide) Hydrogel, Hyoseung Park, Aram Kim, Sumi Bang, Sumi Kim, Eunkyung Shin and In-Sup Noh, The 7th World Congress on Biomimetics, Artificial Muscles and Nano-Bio (BAMN2013), Jeju, Korea, 2013/08/26-2013/08/30
6. Evaluation of Hyaluronic Acid-Chondroitin Sulfate Hydrogel Containing Platelet-Rich Plasma for Cartilage Restoration, Ah Ram Kim, Hyo Seung Park, Beom Chul Kim, Eun Kyung Shin, Soo Yeon Lee, Insup Noh, International Conference on Regenerative Biomedical Materials, International Conference on Regenerative Biomedical Materials, 2013/06/02-2013/06/06,
7. Synthesis and Evaluation of Injectable Hyaluronic Acid-Chondroitin Sulfate Hydrogel Containing Platelet-Rich Plasma for Cartilage Regeneration, Aram Kim, Eunkyung Shin, Myoung Chul Lee, Sung Soo Kim, Insup Noh, Auckland, New Zealand, 2013/12/08- 2013/12/13,

저서

1. 노 인섭, 조직공학과 재생의학 (18장 심혈관계) Cardiovascular system in Tissue Engineering and Regeneration Medicine, Ed. By 유지, 이 일우, 군자출판사, 2002
2. 브라운 유기화학 4판, 유기화학교재연구회, 자유아카데미, 2006
3. 생체재료학, 자유아카데미, 2009
4. 브라운 유기화학 5판, 유기화학교재연구회, 자유아카데미, 2009
5. 조직공학과 재생의학 2판 46장 조직공학 인공혈관, (2009), 군자출판사
6. Handbook of intelligent scaffolds for tissue engineering and regenerative medicine, Pan Stanford Publishing, USA, Ed Gilson Khang, Chapter 9, Hyaluronan-based hydrogel scaffolds, (2012)
7. 조직공학재생의학실험, 조직공학재생의학회(저), 자유아카데미출판사, 2012.12.20 (3부 조직공학기법, 22장 하이드로젤 기반 조직배양기법, 27장 혈관조직재생)
8. Handbook of intelligent scaffolds for tissue engineering and regenerative medicine, Pan Stanford Publishing, USA, Ed Gilson Khang, Chapter 9, Hyaluronic Acid-based Hydrogel as a Scaffold for Tissue engineering, Insup Noh, 2014
9. 고분자공학개론 3판 (공역), 자유아카데미, 2015
10. 브라운의 유기화학 7판 (공역), 사이플러스, 2016
11. 조직공학과 3D 바이오 프린팅(노인섭,최익준), 비즈프레스 2016

보유 특허

1. 키토산-폴리에틸렌옥사이드를 기저로 하는 하이드로젤과 이의 제조방법 [Chitosan-Poly(Ethylene Oxide)-Based Bioactive Hydrogel and Manufacturing Method Therefor] 국내등록 (등록 10-0671965; 등록일: 2007
5. 키토산 또는 히알루론산-폴리에틸렌옥사이드 및 키토산-히알루론산- 폴리에틸렌옥사이드를 기저로 하는 하이드로젤과 이의 제조방법 [Chitosan or Hyaluronic acid-poly(ethylene oxide)-based Hydrogel and Manufacturing Method Therefor], 등록번호 10-0849185 (등록일자 2008.07.23) (발명인: 노인섭, 김건우, 박용두, 이규백, 황순정, 선경, PCT 출원: PCT/KR2006/003383 (2006.08.28)
6. 조직재생을 위한 히알루론산-기초된 주사형 하이드로겔, 등록일 : 2007년 07월 04일, 등록번호 : 10-0737954
7. 골조직침투형 골유착 임플란트, 등록특허 10-0824726(등록일 2008)
8. 사이클로트론 이온 빔 조사에 의한 고분자의 저분자량으로의 조절방법 및 그 응용[Method of control of polymeric molecular weight by irradiation of cyclotron ion beams and its applications therefor], 등록번호((10-0880899; 2009년 1월 21일)
9. 불포화 생물분자를 이용한 키토산 하이드로젤과 이의 제조방법 [Unsaturated Biomolecule Grafting-based Chitosan Hydrogel and Manufacturing Method Therefor], (등록번호 10-0888748-0000 (2009)
10. 리포아마이드가 결합된 고분자 화합물과 이의 제조방법 (출원번호: 10-2009-0035818)-2009.04.24, 등록번호(10-1100803)- PCT/KR2009/006320(2009/11/13); 2009-10-28(유럽-#09-174370.8); (미국 2009-10-29출원 2014-03-10 등록 #12/608,126)
11. 리포산이 결합된 화합물과 이의 제조방법(출원번호: 10-2009-00789)-2009 등록번호 10-1161640 (2012년 06월 26일)
12. 다공성 하이드로젤 및 그 제조방법 (출원번호: 10-2009-0113030), 등록번호: 1178389 (등록일: 2012.08.24.)
13. 아미노살리실산이 결합된 고분자 화합물 (10-2011-0004180), 국내특허출원, (출원일 2011.01.14.), 등록번호 1101242399 (2013.03.06.)
14. 조직고정 기능성의 필름, 노인섭 우정훈 조성연 김수미, 등록번호: 1189459 (등록일자 2012.10.04.) 출원번호, 10-2011-0002415,
15. 트리스(2-카복시에틸)포스핀이 결합된 고분자 화합물 , 노인섭, 조성연, 김수미, 2011년 9월(출원인:등록번호 10-1277286 (등록일자 : 2013.06.14.) PCT 출원일: 2012.09.07./등록 2013-06
16. 생분해성 하이브리드 하이드로젤 및 그 제조방법, 등록번호 101421933 (등록일 2014.07.16.),
17. 고분자-세라믹 하이브리드 젤 및 그것의 제조방법(Polymer-Ceramic Fusion Hybrid Gel And Method For Preparing The Same) 등록번호 10-1657235호 (2016.09.07.)
18. 연조직과 경조직 동시 재생을 위한 다공성, 생분해성 및 서방성 특성을 가진 다층 하이브리드 지지체, 등록번호 10-1655435호 (2016.09.01.), 출원, 출원번호 10-2014-0123042(2014.09.16.)
19. 탄성고분자-세라믹 하이브리드 필름 및 이의 제조방법, 2017년 03월 02일 출원 (10-2017-0027300) (사사-중견핵심, 우선출원권 2016년 10월 06일)
20. 탄성 및 기계적 물성이 우수한 탄성고분자-세라믹 하이브리드 필름 및 이의 제조방법, 2017년 03월 02일 출원 (10-2017-0027301) (사사-중견핵심, 우선출원권 2016년 10월 06일)
21. 기계적 물성이 우수한 고분자-세라믹 하이브리드 필름 및 이의 제조방법, 노인섭, 디판카르 다스, 방수미, 2017년 03월 02일 출원 (10-2017-0027302) (사사-중견핵심, 우선출원권 2016년 10월 06일)

주요 연구 과제 실적

- Development of dermal fillers
- Development of dental scaffolds
- Development of in situ hydrogel for cartilage regeneration
- Development of biodegradable scaffold for vascular graft tissue engineering
- Development of hydrogel for bone tissue regeneration with bioactive molecules delivery

기타(학회활동 등)

1. Korea Society For Biomaterials (vice president)
2. International Conference on Regenerative Biomedical Materials, Program Chairperson, 2013.06, Wuhan, China
3. 조직공학재생의학회-아시아-태평양 부홍보이사, 2014-present
4. 중앙소방기술심의위원회 위원(2011.06.1.-2013.05.31.)
5. 한국조직공학재생의학회 감사(2013-present), 총무이사(2011-2012)
6. 한국화재감식학회 재무이사(2011-present)
7. Organizing Committee of the 2nd TERMIS World Congress 조직위원회 총무위원(Secretary) (2009)
8. The 7th Asian Symposium for Biomedical Materials (ASBM-7) Local Committee Member (2005.10-2006.09)
9. Scientific Program Organizer, The Symposium on the 4th Korea-China Biomaterials and Nano BioTechnology" Jeju-do, Korea (Oct 19-23, 2006)
10. Scientific Organizer, The Symposium on the 5th Korea-China Biomaterials and Nano BioTechnology" Wuhan, China (Oct 12-19, 2007)
11. Guest Editor, Biomedical Material for The Symposium on the 4th Korea-China Biomaterials and Nano BioTechnology" Jeju-do, Korea (2006)

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